During the 1990’s Michigan Vascular Center (MVC) surgeons traveled abroad to learn the new technique of carotid artery stenting. This was long before FDA approval of the devices in the United States. These devices could only be used in the U.S. in patients enrolled in a clinical trial. Michigan Vascular Research Department was created to facilitate clinical trials in our community. This was one of the very first research departments outside of a university setting.
Michigan Vascular Research Department now employs specifically educated staff to manage and operate the department, screening new trials, matching patients with appropriate trials, enrolling patients into trials, and ensuring compliance with all of the regulatory matters.
Why Choose Michigan Vascular For Research?
By participating in a clinical trial a patient gains access to treatments or procedures not yet available in the community. In fact, Michigan Vascular Center has taken a leadership role in bringing state-of-the-art endovascular treatments to Michigan:
- First in Michigan to implant a FDA approved carotid stent manufactured by Guidant, Inc. in September 2004.
- First site in Michigan to implant a superficial femoral artery drug-coated stent manufactured by Cook, Inc. in October 2005.
- First in Michigan to implant a FDA approved abdominal aortic aneurysm pressure monitoring device, manufactured by CardioMEMS in June 2006. This device is placed in the AAA sac at the time of endograft repair in order to remotely measure sac pressure over time.
Since its formation in 1998, we have participated in numerous device, drug and investigator-initiated trials. Without clinical research, medical and surgical innovations could not occur. Because our generation and generations to come rely on today’s clinical research efforts, we are committed to offering innovative and otherwise unavailable treatments to our patients.
Active Trials
CAROTID ARTERY DISEASE
SVS VQI TransCarotid Revascularization Surveillance Project; McLaren
Carotid Artery Stenting using TCAR with Reverse Flow Protection
(open to enrollment)
CREST-2; McLaren
Intense Medical Management (IMM) alone vs. Carotid Stent + IMM vs. Carotid Endarterectomy + IMM
(open to enrollment)
CREST-2 Registry; McLaren
Carotid Artery Stenting (in conjunction with CREST-2 study)
(open to enrollment)
CREST-H; McLaren
(Sub-study of CREST-2); Carotid Stenosis – Hemodynamics
(open to enrollment)
PERIPHERAL ARTERY DISEASE
BEST-CLI; McLaren
Endovascular vs Surgical Repair of PAD in patients with Critical Limb Ischemia
(in follow-up)
TORUS-2; Michigan Vascular Access Center
Superficial Femoral Artery Stenting
(open to enrollment)
BEST Registry
Registry to assess outcomes for patients with Critical Limb Ischemia
(open to enrollment)
AORTIC ANEURYSMAL DISEASE
ANCHOR; McLaren
Hurley, Genesys: Aptus AAA aortic securement system
(in follow-up)
The GREAT Registry; McLaren
Endovascular Treatment of Abdominal Aortic Aneurysms, Outcomes Registry
(in follow-up)
VENOUS STENOSIS
WAVE; Michigan Vascular Access Center
Randomized trial to treat stenosis in dialysis circuit
(open to enrollment)
INVESTIGATOR-INITIATED STUDIES
ASAP: Assess your Risk for Stroke, Abdominal Aortic Aneurysm, and Peripheral Arterial Disease, One-time screening for community meeting high-risk criteria
(open to enrollment)
Incidence of Carotid Stent Fracture Study, Use of X-ray to identify possible fracture in subjects with carotid artery stents
(open to enrollment)
